IUPHAR DATABASE | ABOUT NC-IUPHAR

About NC-IUPHAR

Introduction

"NC-IUPHAR" is the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification. The mission for NC-IUPHAR was initiated in 1987 at the Xth International Congress of Pharmacology. In 1989, the Executive Committee of IUPHAR named Paul Vanhoutte (Hong Kong) as chairman of a revised and enlarged committee. This committee energetically expanded its activities and the number of subcommittees (to 33), eventually producing the first official compendium on the occasion of the XIIIth International Congress of Pharmacology at Munich in 1998. Robert Ruffolo (USA) was Chairman of NC-IUPHAR from 1998-2002. Michael Spedding (France) became Chairman in 2002 and was elected again in 2006 and 2010.

NC-IUPHAR has the objectives of:

Issuing guidelines for the nomenclature and classification of all the (human) biological targets, including all the targets of current and future prescription medicines;
Facilitating the interface between the discovery of new sequences from the Human Genome Project and the designation of the derived entities as functional biological targets and potential drug targets;
Designating polymorphisms and variants which are functionally important;
Developing an authoritative and freely available, global online resource, the IUPHAR database (http://www.iuphar-db.org), which is now accessible via the Guide to PHARMACOLOGY portal (http://www.guidetopharmacology.org), with a remit to:
- provide access to data on all known biological targets;
- enable students and scientists in academia and industry, working in areas related to pharmacology and drug/target research, to exploit the full potential of the considerable amount of information on drug action available in the published literature;
- provide an entry point into the pharmacological literature for basic and clinical scientists from other disciplines;
- provide an integrated educational resource with access to high quality training in the principles of basic and clinical pharmacology and techniques;
- foster innovative drug discovery.

Annual report

For more information about NC-IUPHAR's activities, please download the latest NC-IUPHAR annual report in PDF.

Publications

The publications of NC-IUPHAR are published in Pharmacological Reviews and British Journal of Pharmacology. Click here for a full list.

NC-IUPHAR membership

Chair

Michael Spedding, France

Vice Chairs

Anthony Davenport, UK - Chairman Evolving Pharmacology
Anthony Harmar, UK - Database Chairman
Rick Neubig, USA - GPCRs
Eliot Ohlstein, USA - Editor

Members

Stephen Alexander, UK
Thomas Bonner, USA
William Catterall, USA
Arthur Christopoulos, Australia
Sir Colin T. Dollery, UK
Doriano Fabbro, Switzerland
Kozo Kaibuchi, Japan
Yoshikatsu Kanai, Japan
Vincent Laudet, France
John Peters, UK
Jean-Philippe Pin, France

Ex Officio

Patrick du Souich, Canada (Clinical) - IUPHAR President
Sam Enna, USA - IUPHAR Secretary-General
Urs Ruegg, Switzerland - IUPHAR Treasurer
Joanna Sharman, UK - Database Developer
Adam Pawson, UK - Senior Database Curator
Helen Benson, UK - Database Curator
Elena Faccenda, UK - Database Curator
Veronika Divincova, UK - Project Administrator
Matt Wright, UK - representing HGNC

Past Chairs (ex officio)

Paul Vanhoutte, China
Robert Ruffolo, USA

Corresponding members

Susan Amara, USA
Michel Bouvier, Canada
Stephen Charlton, UK
Moses Chao, USA
Steven L. Colletti, USA
Graham Collingridge, UK
Sue Duckles, USA
Richard Eglen, UK
Steven Foord, UK
Debbie Hay, New Zealand
Allyn Howlett, USA
Franz Hofmann, Germany
Yu Huang, Hong Kong
Ad P. Ijzerman, The Netherlands
Michael F. Jarvis, USA
Terry Kenakin, USA
Janos Kiss, Hungary
Chris Langmead, Australia
Alistair Mathie, UK
Ian McGrath, UK
Graeme Milligan, UK
Stefan Offermanns, Germany
Richard Olsen, USA
Helgi Schiöth, Sweden
Graeme Semple, USA
David Searls, USA
Bart Staels, France
Mary Vore, USA

Clinical Translational Pharmacology Group (core member Sir Colin Dollery)

Ed Bullmore, UK
Robert Dow, UK
Garrett Fitzgerald, USA
Alex Phipps, UK
Patrick du Souich, Canada
David Webb, UK
Don Birkett, Australia