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GPR162

Family: Class A Orphans

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
Tissue Distribution
Expression Datasets
Biologically Significant Variants
General Comments
References
Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 588 12p13 GPR162 G protein-coupled receptor 162
Mouse 7 588 6 F2 Gpr162 G protein-coupled receptor 162
Rat 7 575 4q42 Gpr162 G protein-coupled receptor 162
Previous and Unofficial Names
A-2
GRCA
GPR162
G-protein coupled receptor 162
Gene-rich cluster gene A protein
gene rich cluster, A
probable G-protein coupled receptor 162
Grca_predicted
Gpr162_predicted
LOC362436
G protein-coupled receptor 162
G protein-coupled receptor 162 (predicted)
gene rich cluster, A gene (predicted)
BC031437
Database Links
Ensembl ENSG00000250510 (Hs), ENSMUSG00000038390 (Mm), ENSRNOG00000016143 (Rn)
Entrez Gene 27239 (Hs), 14788 (Mm), 362436 (Rn)
GeneCards GPR162 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gpr162 (Mm)
HomoloGene 8400 (Hs)
Human Protein Reference Database 13608 (Hs)
InterPro Q16538 (Hs), Q3UN16 (Mm)
KEGG Gene hsa:27239 (Hs), mmu:14788 (Mm), rno:362436 (Rn)
PharmGKB Gene PA142671713 (Hs)
PhosphoSitePlus Q16538 (Hs), Q3UN16 (Mm)
Protein Ontology (PRO) PRO:000001638 (Hs)
RefSeq Nucleotide NM_019858 (Hs), NM_013533 (Mm), NM_001108646 (Rn)
RefSeq Protein NP_062832 (Hs), NP_038561 (Mm), NP_001102116 (Rn)
TreeFam ENSG00000250510 (Hs), ENSMUSG00000038390 (Mm), ENSRNOG00000016143 (Rn)
UniGene Hs. 631654 (Hs)
UniProt Q16538 (Hs), Q3UN16 (Mm)
Wikipedia GPR162
Orphan and other 7TM receptors
Tissue Distribution
Central nervous system, lung, sexual organs
Species:  Human
Technique:  Expressed sequence tag
References:  1
Expression Datasets

Click here to show/hide data

Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

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Biologically Significant Variants
R459G
SNP accession:  rs11612427 
Type:  Naturally occurring SNPs.
Species:  Human
References: 
General Comments
GPR162 belongs to the Rhodopsin family of G-protein coupled receptors [1].
Available Assays
DiscoveRx PathHunter® CHO-K1 GPR162 (Orphan) High Expression β-Arrestin Cell Line Human Cat No. 93-0383C2A
DiscoveRx PathHunter® eXpress GPR162 CHO-K1 β-Arrestin (Orphan) GPCR Assay Human Cat No. 93-0383E2ACP1

REFERENCES

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1. Gloriam, DE; Schiöth, HB; Fredriksson, R. (2005) Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. Biochim. Biophys. Acta, 1722 (3): 235-46. [PMID:15777626]

To cite this database page, please use the following:

Wen Chiy Liew.
Class A Orphans: GPR162. Last modified on 05/11/2012. Accessed on 24/05/2013. IUPHAR database (IUPHAR-DB), http://iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=142.


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