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GPR141

Family: Class A Orphans

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
Tissue Distribution
Expression Datasets
References
Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 305 7p14.1 GPR141 G protein-coupled receptor 141
Mouse 7 305 13 A2 Gpr141 G protein-coupled receptor 141
Rat 7 247 17q12.1 Gpr141 G protein-coupled receptor 141
Previous and Unofficial Names
PGR13
GPR141
G-protein coupled receptor 141
G-protein coupled receptor PGR13
probable G-protein coupled receptor 141
axor115
G protein-coupled receptor 141
Database Links
Ensembl ENSG00000187037 (Hs), ENSMUSG00000053101 (Mm), ENSRNOG00000042801 (Rn)
Entrez Gene 353345 (Hs), 353346 (Mm), 291179 (Rn)
GeneCards GPR141 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gpr141 (Mm)
HomoloGene 18771 (Hs)
Human Protein Reference Database 16423 (Hs)
InterPro Q7Z602 (Hs), Q7TQP0 (Mm), Q7TQN5 (Rn)
KEGG Gene hsa:353345 (Hs), mmu:353346 (Mm), rno:291179 (Rn)
OMIM 609045 (Hs)
PharmGKB Gene PA134923895 (Hs)
PhosphoSitePlus Q7Z602 (Hs), Q7TQP0 (Mm)
Protein Ontology (PRO) PRO:000001507 (Hs)
RefSeq Nucleotide NM_181791 (Hs), NM_181754 (Mm), NM_181767 (Rn)
RefSeq Protein NP_861456 (Hs), NP_861419 (Mm), NP_861432 (Rn)
TreeFam ENSG00000187037 (Hs), ENSMUSG00000053101 (Mm), ENSRNOG00000042801 (Rn)
UniGene Hs. 688230 (Hs)
UniProt Q7Z602 (Hs), Q7TQP0 (Mm), Q7TQN5 (Rn)
Wikipedia GPR141
Orphan and other 7TM receptors
Tissue Distribution
Marrow, cancer cells such as human fibrosarcoma HT1080 cells
Species:  Human
Technique:  Expressed sequence tag
References:  1
Expression Datasets

Click here to show/hide data

Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

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Available Assays
DiscoveRx PathHunter® CHO-K1 GPR141 (Orphan) High Expression β-Arrestin Cell Line Human Cat No. 93-0385C2A
DiscoveRx PathHunter® eXpress GPR141 CHO-K1 β-Arrestin (Orphan) GPCR Assay Human Cat No. 93-0385E2ACP1

REFERENCES

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1. Fredriksson, R; Höglund, PJ; Gloriam, DE; Lagerström, MC; Schiöth, HB. (2003) Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. FEBS Lett., 554 (3): 381-8. [PMID:14623098]

To cite this database page, please use the following:

Wen Chiy Liew.
Class A Orphans: GPR141. Last modified on 26/07/2012. Accessed on 22/05/2013. IUPHAR database (IUPHAR-DB), http://iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=131.


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