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GPR62

Family: Class A Orphans

Contents:
Gene and Protein Information
Previous and Unofficial Names
Database Links
Tissue Distribution
General Comments
References
Gene and Protein Information
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 368 3p21.1-p21.9 GPR62 G protein-coupled receptor 62 1
Mouse 7 358 9 F1 Gpr62 G protein-coupled receptor 62
Rat 7 358 8q32 RGD1560166 similar to Probable G-protein coupled receptor 62 (hGPCR8)
Previous and Unofficial Names
KPG_005
MGC26943
GPCR8
LOC501049
RGD1560166_predicted
similar to Probable G-protein coupled receptor 62 (hGPCR8)
similar to Probable G-protein coupled receptor 62 (hGPCR8) (predicted)
4933402E03Rik
Database Links
Ensembl ENSG00000180929 (Hs), ENSMUSG00000091735 (Mm), ENSRNOG00000022567 (Rn)
Entrez Gene 118442 (Hs), 436090 (Mm), 501049 (Rn)
GeneCards GPR62 (Hs)
GenitoUrinary Development Molecular Anatomy Project Gpr62 (Mm)
HomoloGene 50962 (Hs)
Human Protein Reference Database 06078 (Hs)
InterPro Q9BZJ7 (Hs), Q80UC6 (Mm)
KEGG Gene hsa:118442 (Hs), mmu:436090 (Mm), rno:501049 (Rn)
OMIM 606917 (Hs)
PharmGKB Gene PA28906 (Hs)
Protein Ontology (PRO) PRO:000001536 (Hs)
RefSeq Nucleotide NM_080865 (Hs), NM_001159652 (Mm), XM_576464 (Rn)
RefSeq Protein NP_543141 (Hs), NP_001153124 (Mm), XP_576464 (Rn)
TreeFam ENSG00000180929 (Hs), ENSMUSG00000091735 (Mm), ENSRNOG00000022567 (Rn)
UniGene Hs. 232213 (Hs)
UniProt Q9BZJ7 (Hs), Q80UC6 (Mm)
Wikipedia GPR62
Orphan and other 7TM receptors
Tissue Distribution
Brain regions (basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen)
Species:  Human
Technique:  Northern blot
References:  1
Tissue Distribution Comments
Transcripts of GPR62 were not detected in the liver when examined by Northern blot analysis [1].
General Comments
GPR62 has higher expression in the brain, indicating its cognate ligand may be a neurotransmitter [1].

REFERENCES

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1. Lee, DK; George, SR; Cheng, R; Nguyen, T; Liu, Y; Brown, M; Lynch, KR; O'Dowd, BF. (2001) Identification of four novel human G protein-coupled receptors expressed in the brain. Brain Res. Mol. Brain Res., 86 (1-2): 13-22. [PMID:11165367]

To cite this database page, please use the following:

Wen Chiy Liew.
Class A Orphans: GPR62. Last modified on 26/07/2012. Accessed on 19/06/2013. IUPHAR database (IUPHAR-DB), http://iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=111.


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