1. Akanmu, M. A., Ukponmwan, O. E., Katayama, Y. and Honda, K. (2006) Neuropeptide-Y Y2-receptor agonist, PYY3-36 promotes non-rapid eye movement sleep in rat.
Neurosci Res, 54: 165-170.
[PMID:16378653]
2. Allison, S. J., Baldock, P., Sainsbury, A., Enriquez, R., Lee, N. J., Lin, E. J., Klugman, M., During, M., Eisman, J. A., Li, M., Pan, L. C., Herzog, H. and Gardiner, E. M. (2006) Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy-induced bone loss in adult mice.
J Biol Chem, 281: 23436-23444.
[PMID:16785231]
3. Ammar, D. A., Eadie, D. M., Wong, D. J., Ma, Y. Y., Kolakowski, L. F., Yang-Feng, T. L. and Thompson, D. A. (1996) Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene.
Genomics, 38: 392-398.
[PMID:8975716]
4. Baldock, P. A., Sainsbury, A., Couzens, M., Enriquez, R. F., Thomas, G. P., Gardiner, E. M. and Herzog, H. (2002) Hypothalamic Y2 receptors regulate bone formation.
J Clin Invest, 109: 915-921.
[PMID:11927618]
5. Barrios, V. E., Sun, J., Douglass, J. and Toombs, C. F. (1999) Evidence of a specific pancreatic polypeptide receptor in rat arterial smooth muscle.
Peptides, 20: 1107-1113.
[PMID:10499429]
6. Batterham, R. L. and Bloom, S. R. (2003) The gut hormone peptide YY regulates appetite.
Ann N Y Acad Sci, 994: 162-168.
[PMID:12851312]
7. Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., Cone, R. D. and Bloom, S. R. (2002) Gut hormone PYY(3-36) physiologically inhibits food intake.
Nature, 418: 650-654.
[PMID:12167864]
8. Bonaventure, P; Nepomuceno, D; Mazur, C; Lord, B; Rudolph, DA; Jablonowski, JA; Carruthers, NI; Lovenberg, TW. (2004) Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.
J. Pharmacol. Exp. Ther., 308 (3): 1130-7.
[PMID:14617685]
9. Caberlotto, L., Fuxe, K., Rimland, J. M., Sedvall, G. and Hurd, Y. L. (1998) Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain.
Neuroscience, 86: 167-178.
[PMID:9692752]
10. Cabrele, C., Wieland, H. A., Koglin, N., Stidsen, C. and Beck-Sickinger, A. G. (2002) Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor.
Biochemistry, 41: 8043-8049.
[PMID:12069595]
11. Carvajal, C., Dumont, Y., Herzog, H. and Quirion, R. (2006) Emotional behavior in aged neuropeptide Y (NPY) Y2 knockout mice.
J Mol Neurosci, 28: 239-245.
[PMID:16691011]
12. Colmers, W. F., Klapstein, G. J., Fournier, A., St-Pierre, S. and Treherne, K. A. (1991) Presynaptic inhibition by neuropeptide Y in rat hippocampal slice in vitro is mediated by a Y2 receptor.
Br J Pharmacol, 102: 41-44.
[PMID:1646061]
13. Cox, H. M. and Tough, I. R. (2002) Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa.
Br J Pharmacol, 135: 1505-1512.
[PMID:11906964]
14. Cox, H. M., Pollock, E. L., Tough, I. R. and Herzog, H. (2001) Multiple Y receptors mediate pancreatic polypeptide responses in mouse colon mucosa.
Peptides, 22: 445-452.
[PMID:11287100]
15. Doods, H., Gaida, W., Wieland, H. A., Dollinger, H., Schnorrenberg, G., Esser, F., Engel, W., Eberlein, W. and Rudolf, K. (1999) BIIE0246: A selective and high affinity neuropeptide Y Y2 receptor antagonist.
Eur. J. Pharmacol., 384: R3-R5.
[PMID:10611450]
16. Ekstrand, A. J., Cao, R., Bjorndahl, M., Nystrom, S., Jonsson-Rylander, A. C., Hassani, H., Hallberg, B., Nordlander, M. and Cao, Y. (2003) Deletion of neuropeptide Y (NPY) 2 receptor in mice results in blockage of NPY-induced angiogenesis and delayed wound healing.
Proc Natl Acad Sci U S A, 100: 6033-6038.
[PMID:12730369]
17. Ferrier, L., Segain, J. P., Bonnet, C., Cherbut, C., Lehur, P. A., Jarry, A., Galmiche, J. P. and Blottiere, H. M. (2002) Functional mapping of NPY/PYY receptors in rat and human gastro-intestinal tract.
Peptides, 23: 1765-1771.
[PMID:12383864]
18. Fetissov, S. O., Byrne, L. C., Hassani, H., Ernfors, P. and Hökfelt, T. (2004) Characterization of neuropeptide Y Y2 and Y5 receptor expression in the mouse hypothalamus.
J Comp Neurol, 470: 256-265.
[PMID:14755515]
19. Fujimiya, M., Itoh, E., Kihara, N., Yamamoto, I., Fujimura, M. and Inui, A. (2000) Neuropeptide Y induces fasted pattern of duodenal motility via Y(2) receptors in conscious fed rats.
Am J Physiol Gastrointest Liver Physiol, 278: G32-G38.
[PMID:10644559]
20. Félétou, M., Rodriguez, M., Beauverger, P., Germain, M., Imbert, J., Dromaint, S., Macia, C., Bourrienne, A., Henlin, J. M., Nicolas, J. P., Boutin, J. A., Galizzi, J. P., Fauchere, J. L., Canet, E. and Duhault, J. (1998) NPY receptor subtypes involved in the contraction of the proximal colon of the rat.
Regul Pept, 75-76: 221-229.
[PMID:9802413]
21. Gehlert, D. R., Beavers, L. S., Johnson, D., Gackenheimer, S. L., Schober, D. A. and Gadski, R. A. (1996) Expression cloning of a human brain neuropeptide Y Y2 receptor.
Mol Pharmacol, 49: 224-228.
[PMID:8632753]
22. Gerald, C., Walker, M. W., Vaysse, P. J., He, C., Branchek, T. A. and Weinshank, R. L. (1995) Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype.
J Biol Chem, 270: 26758-26761.
[PMID:7592910]
23. Goumain, M., Voisin, T., Lorinet, A. M. and Laburthe, M. (1998) Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon.
Biochem Biophys Res Commun, 247: 52-56.
[PMID:9636652]
24. Goumain, M., Voisin, T., Lorinet, A. M., Ducroc, R., Tsocas, A., Rozé, C., Rouet-Benzineb, P., Herzog, H., Balasubramaniam, A. and Laburthe, M. (2001) The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y(2) receptor: pharmacological evidence and molecular cloning.
Mol Pharmacol, 60: 124-134.
[PMID:11408607]
25. Greco, B. and Carli, M. (2006) Reduced attention and increased impulsivity in mice lacking NPY Y2 receptors: relation to anxiolytic-like phenotype.
Behav Brain Res, 169: 325-334.
[PMID:16529827]
26. Gustafson, E. L., Smith, K. E., Durkin, M. M., Walker, M. W., Gerald, C., Weinshank, R. and Branchek, T. A. (1997) Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system.
Brain Res Mol Brain Res, 46: 223-235.
[PMID:9191097]
27. Hyland, N. P., Sjöberg, F., Tough, I. R., Herzog, H. and Cox, H. M. (2003) Functional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissues.
Br J Pharmacol, 139: 863-871.
[PMID:12813010]
28. Jönsson-Rylander, A. C., Nordlander, M., Svindland, A. and Ilebekk, A. (2003) Distribution of neuropeptide Y Y1 and Y2 receptors in the postmortem human heart.
Peptides, 24: 255-262.
[PMID:12668210]
29. Kaga, T., Fujimiya, M. and Inui, A. (2001) Emerging functions of neuropeptide Y Y(2) receptors in the brain.
Peptides, 22: 501-506.
[PMID:11287107]
30. Kask, A., Rägo, L. and Harro, J. (1998) Anxiolytic-like effect of neuropeptide Y (NPY) and NPY13-36 microinjected into vicinity of locus coeruleus in rats.
Brain Res, 788: 345-348.
[PMID:9555090]
31. Lavebratt, C., Alpman, A., Persson, B., Arner, P. and Hoffstedt, J. (2006) Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men.
Int J Obes (Lond), 30: 453-459.
[PMID:16331299]
32. Lee, E. W., Grant, D. S., Movafagh, S. and Zukowska, Z. (2003) Impaired angiogenesis in neuropeptide Y (NPY)-Y2 receptor knockout mice.
Peptides, 24: 99-106.
[PMID:12576090]
33. Lee, E. W., Michalkiewicz, M., Kitlinska, J., Kalezic, I., Switalska, H., Yoo, P., Sangkharat, A., Ji, H., Li, L., Michalkiewicz, T., Ljubisavljevic, M., Johansson, H., Grant, D. S. and Zukowska, Z. (2003) Neuropeptide Y induces ischemic angiogenesis and restores function of ischemic skeletal muscles.
J Clin Invest, 111: 1853-1862.
[PMID:12813021]
34. Lin, S., Boey, D. and Herzog, H. (2004) NPY and Y receptors: lessons from transgenic and knockout models.
Neuropeptides, 38: 189-200.
[PMID:15337371]
35. Lutz, C. M., Frankel, W. N., Richards, J. E. and Thompson, D. A. (1997) Neuropeptide Y receptor genes on human chromosome 4q31-q32 map to conserved linkage groups on mouse chromosomes 3 and 8.
Genomics, 41: 498-500.
[PMID:9169155]
36. Lynch, J. W., Lemos, V. S., Bucher, B., Stoclet, J. C. and Takeda, K. (1994) A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line.
J Biol Chem, 269: 8226-8233.
[PMID:8132547]
37. Misra, S., Murthy, K. S., Zhou, H. and Grider, J. R. (2004) Coexpression of Y1, Y2, and Y4 receptors in smooth muscle coupled to distinct signaling pathways.
J Pharmacol Exp Ther, 311: 1154-1162.
[PMID:15308651]
38. Nakajima, M., Inui, A., Asakawa, A., Momose, K., Ueno, N., Teranishi, A., Baba, S. and Kasuga, M. (1998) Neuropeptide Y produces anxiety via Y2-type receptors.
Peptides, 19: 359-363.
[PMID:9493869]
39. Nakamura, M., Aoki, Y. and Hirano, D. (1996) Cloning and functional expression of a cDNA encoding a mouse type 2 neuropeptide Y receptor.
Biochim Biophys Acta, 1284: 134-137.
[PMID:8914576]
40. Naveilhan, P., Canals, J. M., Arenas, E. and Ernfors, P. (2001) Distinct roles of the Y1 and Y2 receptors on neuropeptide Y-induced sensitization to sedation.
J Neurochem, 78: 1201-1207.
[PMID:11579129]
41. Parker, R. M. and Herzog, H. (1999) Regional distribution of Y-receptor subtype mRNAs in rat brain.
Eur J Neurosci, 11: 1431-1448.
[PMID:10103138]
42. Pheng, L. H., Perron, A., Quirion, R., Cadieux, A., Fauchere, J. L., Dumont, Y. and Regoli, D. (1999) Neuropeptide Y-induced contraction is mediated by neuropeptide Y Y2 and Y4 receptors in the rat colon.
Eur J Pharmacol, 374: 85-91.
[PMID:10422644]
43. Redrobe, J. P., Dumont, Y., Herzog, H. and Quirion, R. (2003) Neuropeptide Y (NPY) Y2 receptors mediate behaviour in two animal models of anxiety: evidence from Y2 receptor knockout mice.
Behav Brain Res, 141: 251-255.
[PMID:12742262]
44. Redrobe, J. P., Dumont, Y., Herzog, H. and Quirion, R. (2004) Characterization of neuropeptide Y, Y(2) receptor knockout mice in two animal models of learning and memory processing.
J Mol Neurosci, 22: 159-166.
[PMID:14997009]
45. Rimland, J. M., Seward, E. P., Humbert, Y., Ratti, E., Trist, D. G. and North, R. A. (1996) Coexpression with potassium channel subunits used to clone the Y2 receptor for neuropeptide Y.
Mol Pharmacol, 49: 387-390.
[PMID:8643076]
46. Rose, P. M., Fernandes, P., Lynch, J. S., Frazier, S. T., Fisher, S. M., Kodukula, K., Kienzle, B. and Seethala, R. (1995) Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.
J Biol Chem, 270: 22661-22664.
[PMID:7559383]
47. Sainsbury, A., Schwarzer, C., Couzens, M., Fetissov, S., Furtinger, S., Jenkins, A., Cox, H. M., Sperk, G., Hökfelt, T. and Herzog, H. (2002) Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice.
Proc Natl Acad Sci U S A, 99: 8938-8943.
[PMID:12072562]
48. Sajdyk, T. J., Schober, D. A., Smiley, D. L. and Gehlert, D. R. (2002) Neuropeptide Y-Y2 receptors mediate anxiety in the amygdala.
Pharmacol Biochem Behav, 71: 419-423.
[PMID:11830176]
49. Scott, V., Kimura, N., Stark, J. A. and Luckman, S. M. (2005) Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour.
J Neuroendocrinol, 17: 452-457.
[PMID:15946163]
50. Shigeri, Y. and Fujimoto, M. (1994) Y2 receptors for neuropeptide Y are coupled to three intracellular signal transduction pathways in a human neuroblastoma cell line.
J Biol Chem, 269: 8842-8848.
[PMID:8132619]
51. Soscia, S. J. and Harrington, M. E. (2005) Neuropeptide Y does not reset the circadian clock in NPY Y2-/- mice.
Neurosci Lett, 373: 175-178.
[PMID:15619538]
52. Stanic, D., Brumovsky, P., Fetissov, S., Shuster, S., Herzog, H. and Hökfelt, T. (2006) Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminals.
J Comp Neurol, 499: 357-390.
[PMID:16998904]
53. Thiele, T. E., Naveilhan, P. and Ernfors, P. (2004) Assessment of ethanol consumption and water drinking by NPY Y(2) receptor knockout mice.
Peptides, 25: 975-983.
[PMID:15203244]
54. Thorsell, A., Rimondini, R. and Heilig, M. (2002) Blockade of central neuropeptide Y (NPY) Y2 receptors reduces ethanol self-administration in rats.
Neurosci Lett, 332: 1-4.
[PMID:12377370]
55. Tschenett, A., Singewald, N., Carli, M., Balducci, C., Salchner, P., Vezzani, A., Herzog, H. and Sperk, G. (2003) Reduced anxiety and improved stress coping ability in mice lacking NPY-Y2 receptors.
Eur J Neurosci, 18: 143-148.
[PMID:12859347]
56. Wultsch, T., Painsipp, E., Donner, S., Sperk, G., Herzog, H., Peskar, B. A. and Holzer, P. (2006) Selective increase of dark phase water intake in neuropeptide-Y Y2 and Y4 receptor knockout mice.
Behav Brain Res, 168: 255-260.
[PMID:16364461]
57. Zukowska-Grojec, Z., Karwatowska-Prokopczuk, E., Rose, W., Rone, J., Movafagh, S., Ji, H., Yeh, Y., Chen, W. T., Kleinman, H. K., Grouzmann, E. and Grant, D. S. (1998) Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium.
Circ Res, 83: 187-195.
[PMID:9686758]