LIGAND-GATED ION CHANNEL SUBUNITS
Voltage-gated ion channel subunits | Download ion channel data as an Excel file
| 5-HT3 receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3A |
HTR3A |
Htr3a |
Htr3a |
|
| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3B |
HTR3B |
Htr3b |
Htr3b |
|
| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3C |
HTR3C |
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| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3D |
HTR3D |
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| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3E |
HTR3E |
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| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3AB | ||||
| 5-HT3 receptors | 5-hydroxytryptamine | 5-HT3A | ||||
| GABAA receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| GABAA receptors | GABA | α1 |
GABRA1 |
Gabra1 |
Gabra1 |
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| GABAA receptors | GABA | α2 |
GABRA2 |
Gabra2 |
Gabra2 |
|
| GABAA receptors | GABA | α3 |
GABRA3 |
Gabra3 |
Gabra3 |
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| GABAA receptors | GABA | α4 |
GABRA4 |
Gabra4 |
Gabra4 |
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| GABAA receptors | GABA | α5 |
GABRA5 |
Gabra5 |
Gabra5 |
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| GABAA receptors | GABA | α6 |
GABRA6 |
Gabra6 |
Gabra6 |
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| GABAA receptors | GABA | β1 |
GABRB1 |
Gabrb1 |
Gabrb1 |
|
| GABAA receptors | GABA | β2 |
GABRB2 |
Gabrb2 |
Gabrb2 |
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| GABAA receptors | GABA | β3 |
GABRB3 |
Gabrb3 |
Gabrb3 |
|
| GABAA receptors | GABA | γ1 |
GABRG1 |
Gabrg1 |
Gabrg1 |
|
| GABAA receptors | GABA | γ2 |
GABRG2 |
Gabrg2 |
Gabrg2 |
|
| GABAA receptors | GABA | γ3 |
GABRG3 |
Gabrg3 |
Gabrg3 |
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| GABAA receptors | GABA | δ |
GABRD |
Gabrd |
Gabrd |
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| GABAA receptors | GABA | ε |
GABRE |
Gabre |
Gabre |
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| GABAA receptors | GABA | θ |
GABRQ |
Gabrq |
Gabrq |
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| GABAA receptors | GABA | π |
GABRP |
Gabrp |
Gabrp |
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| GABAA receptors | GABA | ρ1 |
GABRR1 |
Gabrr1 |
Gabrr1 |
|
| GABAA receptors | GABA | ρ2 |
GABRR2 |
Gabrr2 |
Gabrr2 |
|
| GABAA receptors | GABA | ρ3 |
GABRR3 |
Gabrr3 |
Gabrr3 |
|
| Glycine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| Glycine receptors | glycine | α1 |
GLRA1 |
Glra1 |
Glra1 |
|
| Glycine receptors | glycine | α2 |
GLRA2 |
Glra2 |
Glra2 |
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| Glycine receptors | glycine | α3 |
GLRA3 |
Glra3 |
Glra3 |
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| Glycine receptors | glycine | α4 (pseudogene in humans) |
GLRA4 |
Glra4 |
Glra4 |
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| Glycine receptors | glycine | β |
GLRB |
Glrb |
Glrb |
|
| Glycine receptors | glycine | Glycine Receptor (All subtypes) | ||||
| Ionotropic glutamate receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| Ionotropic glutamate receptors | glutamate | GluA1 |
GRIA1 |
Gria1 |
Gria1 |
|
| Ionotropic glutamate receptors | glutamate | GluA2 |
GRIA2 |
Gria2 |
Gria2 |
|
| Ionotropic glutamate receptors | glutamate | GluA3 |
GRIA3 |
Gria3 |
Gria3 |
|
| Ionotropic glutamate receptors | glutamate | GluA4 |
GRIA4 |
Gria4 |
Gria4 |
|
| Ionotropic glutamate receptors | glutamate | GluD1 |
GRID1 |
Grid1 |
Grid1 |
|
| Ionotropic glutamate receptors | glutamate | GluD2 |
GRID2 |
Grid2 |
Grid2 |
|
| Ionotropic glutamate receptors | glutamate | GluK1 |
GRIK1 |
Grik1 |
Grik1 |
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| Ionotropic glutamate receptors | glutamate | GluK2 |
GRIK2 |
Grik2 |
Grik2 |
|
| Ionotropic glutamate receptors | glutamate | GluK3 |
GRIK3 |
Grik3 |
Grik3 |
|
| Ionotropic glutamate receptors | glutamate | GluK4 |
GRIK4 |
Grik4 |
Grik4 |
|
| Ionotropic glutamate receptors | glutamate | GluK5 |
GRIK5 |
Grik5 |
Grik5 |
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| Ionotropic glutamate receptors | glutamate | GluN1 |
GRIN1 |
Grin1 |
Grin1 |
|
| Ionotropic glutamate receptors | glutamate | GluN2A |
GRIN2A |
Grin2a |
Grin2a |
|
| Ionotropic glutamate receptors | glutamate | GluN2B |
GRIN2B |
Grin2b |
Grin2b |
|
| Ionotropic glutamate receptors | glutamate | GluN2C |
GRIN2C |
Grin2c |
Grin2c |
|
| Ionotropic glutamate receptors | glutamate | GluN2D |
GRIN2D |
Grin2d |
Grin2d |
|
| Ionotropic glutamate receptors | glutamate | GluN3A |
GRIN3A |
Grin3a |
Grin3a |
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| Ionotropic glutamate receptors | glutamate | GluN3B |
GRIN3B |
Grin3b |
Grin3b |
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| Nicotinic acetylcholine receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| Nicotinic acetylcholine receptors | acetylcholine | α1 |
CHRNA1 |
Chrna1 |
Chrna1 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α2 |
CHRNA2 |
Chrna2 |
Chrna2 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α3 |
CHRNA3 |
Chrna3 |
Chrna3 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α4 |
CHRNA4 |
Chrna4 |
Chrna4 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α5 |
CHRNA5 |
Chrna5 |
Chrna5 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α6 |
CHRNA6 |
Chrna6 |
Chrna6 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α7 |
CHRNA7 |
Chrna7 |
Chrna7 |
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| Nicotinic acetylcholine receptors | α8 (avian) | |||||
| Nicotinic acetylcholine receptors | acetylcholine | α9 |
CHRNA9 |
Chrna9 |
Chrna9 |
|
| Nicotinic acetylcholine receptors | acetylcholine | α10 |
CHRNA10 |
Chrna10 |
Chrna10 |
|
| Nicotinic acetylcholine receptors | acetylcholine | β1 |
CHRNB1 |
Chrnb1 |
Chrnb1 |
|
| Nicotinic acetylcholine receptors | acetylcholine | β2 |
CHRNB2 |
Chrnb2 |
Chrnb2 |
|
| Nicotinic acetylcholine receptors | acetylcholine | β3 |
CHRNB3 |
Chrnb3 |
Chrnb3 |
|
| Nicotinic acetylcholine receptors | acetylcholine | β4 |
CHRNB4 |
Chrnb4 |
Chrnb4 |
|
| Nicotinic acetylcholine receptors | acetylcholine | γ |
CHRNG |
Chrng |
Chrng |
|
| Nicotinic acetylcholine receptors | acetylcholine | δ |
CHRND |
Chrnd |
Chrnd |
|
| Nicotinic acetylcholine receptors | acetylcholine | ε |
CHRNE |
Chrne |
Chrne |
|
| P2X receptors | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| P2X receptors | ATP | P2X1 |
P2RX1 |
P2rx1 |
P2rx1 |
|
| P2X receptors | ATP | P2X2 |
P2RX2 |
P2rx2 |
P2rx2 |
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| P2X receptors | ATP | P2X3 |
P2RX3 |
P2rx3 |
P2rx3 |
|
| P2X receptors | ATP | P2X4 |
P2RX4 |
P2rx4 |
P2rx4 |
|
| P2X receptors | ATP | P2X5 |
P2RX5 |
P2rx5 |
P2rx5 |
|
| P2X receptors | ATP | P2X6 |
P2RX6 |
P2rx6 |
P2rx6 |
|
| P2X receptors | ATP | P2X7 |
P2RX7 |
P2rx7 |
P2rx7 |
|
| ZAC | ||||||
| Family name | Ligand | Official IUPHAR receptor name | Human gene symbol | Rat gene symbol | Mouse gene symbol | Comment |
| ZAC | Zn++ | ZAC |
ZACN |
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